Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[2-Oxo-3-(S)-(5-pyridin-4-ylthiophene-2-ylsulfonylamino)-pyrrolidin-1-ylmethyl]benzamidine
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 PubChem ID
CID: 10837478
SID: 15878940
Canonical SMILES
NC(=N)c1cccc(CN2CC[C@H](NS(=O)(=O)c3ccc(s3)-c3ccncc3)C2=O)c1
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Compound Formula C21H21N5O3S2
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 299 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 40.8 nM
2 IC50 = 42.9 nM
3 IC50 = 46.1 nM
4 IC50 = 46.5 nM
5 IC50 = 49.4 nM
6 IC50 = 49.8 nM
7 IC50 = 50.1 nM
8 IC50 = 53.5 nM
9 IC50 = 58.5 nM
10 IC50 = 60.8 nM
11 IC50 = 61.8 nM
12 IC50 = 63.9 nM
13 Kd = 192.45 nM
14 Ki = 55 nM