Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-4-chloro-N-(1-(2-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenylamino)-2-oxoethyl)pyrrolidin-3-yl)cyclopenta-1,3-dienecarboxamide
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 PubChem ID
CID: 42628060
SID: 81082709
Canonical SMILES
Fc1cc(ccc1NC(=O)CN1CC[C@H](C1)NC(=O)c1ccc(Cl)s1)-n1ccccc1=O
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Compound Formula C22H20ClFN4O3S
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 14.03 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.67 nM
2 IC50 = 1.73 nM
3 IC50 = 1.75 nM
4 IC50 = 1.76 nM
5 IC50 = 1.83 nM
6 IC50 = 1.85 nM
7 IC50 = 1.89 nM
8 IC50 = 1.9 nM
9 IC50 = 1.98 nM
10 IC50 = 2.04 nM
11 IC50 = 2.05 nM
12 IC50 = 2.07 nM
13 Ki = 8 nM