Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)nicotinamide
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 PubChem ID
CID: 11539245
SID: 16641356
Canonical SMILES
Clc1ccc(cn1)C(=O)NC[C@H]1CN(C(=O)O1)c1ccc(cc1)N1CCOCC1=O
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Compound Formula C20H19ClN4O5
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 182.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 55.7 nM
2 IC50 = 63.6 nM
3 IC50 = 73.4 nM
4 IC50 = 74.3 nM
5 IC50 = 74.6 nM
6 IC50 = 75.8 nM
7 IC50 = 77.4 nM
8 IC50 = 83.4 nM
9 IC50 = 87 nM
10 IC50 = 87.5 nM
11 IC50 = 90.5 nM
12 IC50 = 94 nM
13 IC50 = 96.1 nM
14 Kd = 53.94 nM