Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-Chloro-N-({(5S)-3-[4-(dimethylamino)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide
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 PubChem ID
CID: 11523750
SID: 16625732
Canonical SMILES
CN(C)c1ccc(cc1)N1C[C@H](CNC(=O)c2ccc(Cl)s2)OC1=O
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Compound Formula C17H18ClN3O3S
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 13.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.15 nM
2 IC50 = 3.88 nM
3 IC50 = 4.35 nM
4 IC50 = 4.39 nM
5 IC50 = 4.68 nM
6 IC50 = 4.97 nM
7 IC50 = 5.1 nM
8 IC50 = 5.86 nM
9 IC50 = 5.87 nM
10 IC50 = 5.96 nM
11 IC50 = 6.15 nM
12 IC50 = 6.75 nM
13 IC50 = 74 nM
14 Kd = 15.61 nM