Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-chloro-N-(1-(2-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenylamino)-2-oxoethyl)-1H-1,2,4-triazol-3-yl)cyclopenta-1,3-dienecarboxamide
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 PubChem ID
CID: 11561914
SID: 16664125
Canonical SMILES
Fc1cc(ccc1NC(=O)Cn1cnc(NC(=O)c2ccc(Cl)s2)n1)-n1ccccc1=O
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Compound Formula C20H14ClFN6O3S
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 13.67 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.19 nM
2 IC50 = 1.25 nM
3 IC50 = 1.26 nM
4 IC50 = 1.28 nM
5 IC50 = 1.35 nM
6 IC50 = 1.41 nM
7 IC50 = 1.46 nM
8 IC50 = 1.53 nM
9 IC50 = 1.55 nM
10 IC50 = 1.66 nM
11 IC50 = 1.72 nM
12 IC50 = 1.73 nM
13 Kd = 5.855 nM
14 Ki = 6 nM