Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[(3-carbamimidoylphenyl)methyl]-N-[(3,5-dimethylphenyl)methyl]-4-methyl-1H-indole-2-carboxamide
    Show/Hide
 PubChem ID
CID: 446984
SID: 14957750
Canonical SMILES
Cc1cc(C)cc(CNC(=O)c2cc3c(C)cccc3n2Cc2cccc(c2)C(N)=N)c1
    Show/Hide
Compound Formula C27H28N4O
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 120.33 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 57 nM
2 IC50 = 57.3 nM
3 IC50 = 64.5 nM
4 IC50 = 67.7 nM
5 IC50 = 68.4 nM
6 IC50 = 69.9 nM
7 IC50 = 72.5 nM
8 IC50 = 74.5 nM
9 IC50 = 76.3 nM
10 IC50 = 78.4 nM
11 IC50 = 81.2 nM
12 Kd = 23.05 nM
13 Ki = 9 nM