Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxopyrrolidin-3-yl]thieno[3,2-b]pyridine-2-sulfonamide
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 PubChem ID
CID: 445480
SID: 15058032
Canonical SMILES
Nc1nccc2ccc(CN3CC[C@H](NS(=O)(=O)c4cc5ncccc5s4)C3=O)cc12
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Compound Formula C21H19N5O3S2
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 106.77 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 17.6 nM
2 IC50 = 27.1 nM
3 IC50 = 31.5 nM
4 IC50 = 32 nM
5 IC50 = 32.4 nM
6 IC50 = 37 nM
7 IC50 = 37.4 nM
8 IC50 = 37.7 nM
9 IC50 = 42.1 nM
10 IC50 = 42.7 nM
11 IC50 = 42.9 nM
12 IC50 = 43.7 nM
13 Kd = 85.35 nM
14 Ki = 22 nM