Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE
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 PubChem ID
CID: 447362
SID: 14882618
Canonical SMILES
NC(=N)c1ccc(CN2CCN(CC2=O)S(=O)(=O)c2cc3ccc(Cl)cc3s2)cc1
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Compound Formula C20H19ClN4O3S2
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 265 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.23 nM
2 IC50 = 1.45 nM
3 IC50 = 1.51 nM
4 IC50 = 1.53 nM
5 IC50 = 1.54 nM
6 IC50 = 1.61 nM
7 IC50 = 1.64 nM
8 IC50 = 1.69 nM
9 IC50 = 1.74 nM
10 IC50 = 1.83 nM
11 IC50 = 1.91 nM
12 IC50 = 1.92 nM
13 Kd = 2.281 nM
14 Ki = 1 nM
15 Ki = 1.3 nM