Brief Information of the Compound and Protein
Compound Name
(3S,8aS)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydropyrrolo[1,2- a]pyrazin-1(2H)-one
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PubChem ID
CID: 53630923
Canonical SMILES
COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1CN2CCC[C@H]2C(=O)N1
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Compound Formula C23H22Cl2FN5O3
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase VEGFR family
Uniprot ID
P17948
Gene Name
FLT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 50 nM
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   LI
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