Brief Information of the Compound and Protein
Compound Name
US10022352, Compound 320
    Show/Hide
PubChem ID
CID: 46199648
SID: 96053598
Canonical SMILES
CC(C)(CO)c1cc2cc(NC(=O)C3(CC3)c3ccc4OC(F)(F)Oc4c3)c(F)cc2[nH]1
    Show/Hide
Compound Formula C23H21F3N2O4
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
>
Other ion channel
>
Chloride channel
>
Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 4315 nM
   TI
   LI
   LO
   TS