Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10022352, Compound 313
    Show/Hide
 PubChem ID
CID: 46199866
SID: 96053829
Canonical SMILES
CC(C)(C)c1cc2c(C#N)c(NC(=O)C3(CC3)c3ccc4OC(F)(F)Oc4c3)ccc2[nH]1
    Show/Hide
Compound Formula C24H21F2N3O3
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
>
Other ion channel
>
Chloride channel
>
Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 283.5 nM
   TI
   LI
   LO
   TS