Brief Information of the Compound and Protein
Compound Name
N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-2-(3-oxo-3,4-dihydroquinoxalin-5-yloxy)acetamide
    Show/Hide
PubChem ID
CID: 90328812
Canonical SMILES
O=C(COc1cccc2ncc(=O)[nH]c12)NCC(O)CN1CCc2ccccc2C1
    Show/Hide
Compound Formula C22H24N4O4
Compound Structure
Protein Name
Protein arginine N-methyltransferase 5
Protein Classification
Epigenetic regulator
>
Writer
>
Protein methyltransferase
>
Protein arginine methyltransferase
Uniprot ID
O14744
Gene Name
PRMT5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000114 Z-138 Homo sapiens (Human)  1
1
EC50 = 1001 nM
   TI
   LI
   LO
   TS