Brief Information of the Compound and Protein
Compound Name
(R)-1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(quinolin-8-yl)phenoxy)propan-2-ol
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PubChem ID
CID: 86729297
Canonical SMILES
O[C@@H](COc1cccc(c1)-c1cccc2cccnc12)CN1CCc2ccccc2C1
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Compound Formula C27H26N2O2
Compound Structure
Protein Name
Protein arginine N-methyltransferase 5
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
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Protein arginine methyltransferase
Uniprot ID
O14744
Gene Name
PRMT5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000114 Z-138 Homo sapiens (Human)  1
1
EC50 = 101 nM
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