Brief Information of the Compound and Protein
Compound Name
2-(2-(N,N-dimethylsulfamoyl)phenoxy)-N-(2-hydroxy-3-(isoindolin-2-yl)propyl)acetamide
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PubChem ID
CID: 76902225
Canonical SMILES
CN(C)S(=O)(=O)c1ccccc1OCC(=O)NCC(O)CN1Cc2ccccc2C1
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Compound Formula C21H27N3O5S
Compound Structure
Protein Name
Protein arginine N-methyltransferase 5
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
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Protein arginine methyltransferase
Uniprot ID
O14744
Gene Name
PRMT5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000114 Z-138 Homo sapiens (Human)  1
1
EC50 = 101 nM
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