Brief Information of the Compound and Protein
Compound Name
(4-((5-(4-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropoxy)phenyl)-1H-pyrazol-1-yl)methyl)phenyl)(pyrrolidin-1-yl)methanone
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PubChem ID
CID: 90242099
Canonical SMILES
OC(COc1ccc(cc1)-c1ccnn1Cc1ccc(cc1)C(=O)N1CCCC1)CN1CCc2ccccc2C1
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Compound Formula C33H36N4O3
Compound Structure
Protein Name
Protein arginine N-methyltransferase 5
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
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Protein arginine methyltransferase
Uniprot ID
O14744
Gene Name
PRMT5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000114 Z-138 Homo sapiens (Human)  1
1
EC50 = 1001 nM
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