Brief Information of the Compound and Protein
Compound Name
4-(4-chlorophenyl)-1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)piperazin-2-one
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PubChem ID
CID: 76684524
Canonical SMILES
OC(CN1CCc2ccccc2C1)CN1CCN(CC1=O)c1ccc(Cl)cc1
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Compound Formula C22H26ClN3O2
Compound Structure
Protein Name
Protein arginine N-methyltransferase 5
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
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Protein arginine methyltransferase
Uniprot ID
O14744
Gene Name
PRMT5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000114 Z-138 Homo sapiens (Human)  1
1
EC50 = 101 nM
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