Brief Information of the Compound and Protein
Compound Name
N-(2-hydroxy-3-(isoindolin-2-yl)propyl)-3-(pyridin-2-yl)benzamide
    Show/Hide
PubChem ID
CID: 76902223
Canonical SMILES
OC(CNC(=O)c1cccc(c1)-c1ccccn1)CN1Cc2ccccc2C1
    Show/Hide
Compound Formula C23H23N3O2
Compound Structure
Protein Name
Protein arginine N-methyltransferase 5
Protein Classification
Epigenetic regulator
>
Writer
>
Protein methyltransferase
>
Protein arginine methyltransferase
Uniprot ID
O14744
Gene Name
PRMT5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000114 Z-138 Homo sapiens (Human)  1
1
EC50 = 1001 nM
   TI
   LI
   LO
   TS