Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[2-hydroxy-3-methyl-4-[[4-[4-(2H-tetrazol-5-yl)pyridin-2-yl]oxyphenyl]methoxy]phenyl]ethanone
    Show/Hide
 PubChem ID
CID: 11596869
SID: 16699515
Canonical SMILES
CC(=O)c1ccc(OCc2ccc(Oc3cc(ccn3)-c3nn[nH]n3)cc2)c(C)c1O
    Show/Hide
Compound Formula C22H19N5O4
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 1
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
Q13255
Gene Name
GRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000125 MCB3901
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  3
1
EC50 > 12500 nM
   TI
   LI
   LO
   TS
2
EC50 > 25000 nM
   TI
   LI
   LO
   TS
3
IC50 > 8000 nM
   TI
   LI
   LO
   TS