Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[2-hydroxy-4-[[3-[5-(2H-tetrazol-5-yl)pyridin-2-yl]oxyphenyl]methoxy]-3-(trifluoromethyl)phenyl]ethanone
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 PubChem ID
CID: 59599580
Canonical SMILES
CC(=O)c1ccc(OCc2cccc(Oc3ccc(cn3)-c3nn[nH]n3)c2)c(c1O)C(F)(F)F
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Compound Formula C22H16F3N5O4
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000125 MCB3901
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  1
1
EC50 = 17.9 nM
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   LI
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   TS