Brief Information of the Compound and Protein
Compound Name
(8S,9S,11S,13S,14S,17S)-11,17-dihydroxy-13-methyl-17-(3-methylbut-1-ynyl)-N-(2-methylpyridin-3-yl)-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3-carboxamide
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PubChem ID
CID: 134141623
Canonical SMILES
CC(C)C#C[C@]1(O)CC[C@H]2[C@@H]3CCc4cc(ccc4[C@H]3[C@@H](O)C[C@]12C)C(=O)Nc1cccnc1C
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Compound Formula C30H36N2O3
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  2
1
EC50 > 5000 nM
   TI
   LI
   LO
   TS
2
IC50 = 37 nM
   TI
   LI
   LO
   TS