Brief Information of the Compound and Protein
Compound Name
(1R,12R,13S,17R,21S)-6-chloro-12-ethyl-18-propyl-10,18-diazapentacyclo[11.7.1.02,11.04,9.017,21]henicosa-2(11),3,5,7,9-pentaene
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PubChem ID
CID: 134147710
Canonical SMILES
CCCN1CC[C@@H]2[C@@H]3[C@H](CCC[C@@H]13)[C@@H](CC)c1nc3ccc(Cl)cc3cc21
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Compound Formula C24H31ClN2
Compound Structure
Protein Name
Kappa-type opioid receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
Ki = 372 nM
   TI
   LI
   LO
   TS