Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,2R,3S,4S,5R,6R)-2-amino-3-[(3,4-dichlorophenyl)methoxy]-4-[(2-methyl-1,2,4-triazol-3-yl)sulfanyl]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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 PubChem ID
CID: 86695984
Canonical SMILES
Cn1ncnc1S[C@H]1[C@H]2[C@@H]([C@H]2[C@@](N)([C@@H]1OCc1ccc(Cl)c(Cl)c1)C(O)=O)C(O)=O
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Compound Formula C18H18Cl2N4O5S
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000125 MCB3901
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  1
1
IC50 = 19.9 nM
   TI
   LI
   LO
   TS