Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1S,2S,4R,5R,6R)-2-amino-4-hydroxybicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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 PubChem ID
CID: 70052526
Canonical SMILES
N[C@]1(C[C@@H](O)[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O
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Compound Formula C8H11NO5
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000125 MCB3901
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  2
1
EC50 = 7.6 nM
   TI
   LI
   LO
   TS
2
Ki = 166 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8.6 nM