Brief Information of the Compound and Protein
Compound Name
(8-amino-3-(2-methyl-3-(trifluoromethyl)benzyl)-6-morpholinoimidazo[1,2-b]pyridazin-2-yl)methanol methanesulfonate
    Show/Hide
PubChem ID
CID: 134136890
Canonical SMILES
CS(=O)(=O)O.Cc1c(Cc2c(CO)nc3c(N)cc(N4CCOCC4)nn23)cccc1C(F)(F)F
    Show/Hide
Compound Formula C21H26F3N5O5S
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  2
1
IC50 = 38 nM
   TI
   LI
   LO
   TS
2
IC50 = 46 nM
   TI
   LI
   LO
   TS