Brief Information of the Compound and Protein
Compound Name
8-(1H-imidazol-5-yl)-2-methyl-N-[2-methyl-3-(trifluoromethyl)phenyl]-6-morpholin-4-ylimidazo[1,2-b]pyridazin-3-amine
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PubChem ID
CID: 137167632
Canonical SMILES
Cc1nc2c(cc(nn2c1Nc1cccc(c1C)C(F)(F)F)N1CCOCC1)-c1cnc[nH]1
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Compound Formula C22H22F3N7O
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  2
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
2
IC50 = 12 nM
   TI
   LI
   LO
   TS