Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R)-N-[4-chloro-3-[1-methyl-5-(trifluoromethoxy)benzimidazol-2-yl]phenyl]-2-[(5R,8S)-2,5-dimethyl-5,6,7,8-tetrahydroquinolin-8-yl]propanamide
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 PubChem ID
CID: 134151929
Canonical SMILES
C[C@H]([C@@H]1CC[C@@H](C)c2ccc(C)nc12)C(=O)Nc1ccc(Cl)c(c1)-c1nc2cc(OC(F)(F)F)ccc2n1C
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Compound Formula C29H28ClF3N4O2
Compound Structure
Protein Name
 Protein Info 
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000426 Shh Light II
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 84.5 nM
   TI
   LI
   LO
   TS