Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,4S,5R,8S,9S,12R)-N-(4-chloro-3-pyridin-2-ylphenyl)-1,5,9-trimethyl-10,13,14,15-tetraoxatetracyclo[9.3.1.04,12.08,12]pentadecane-9-carboxamide
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 PubChem ID
CID: 134143997
Canonical SMILES
C[C@@H]1CC[C@H]2[C@](C)(OC3O[C@@]4(C)CC[C@@H]1[C@@]23OO4)C(=O)Nc1ccc(Cl)c(c1)-c1ccccn1
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Compound Formula C26H29ClN2O5
Compound Structure
Protein Name
 Protein Info 
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000426 Shh Light II
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS