Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(dimethylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
    Show/Hide
 PubChem ID
CID: 134157788
Canonical SMILES
CNC(=O)[C@@]12C[C@@H]1[C@H]([C@H](O)[C@@H]2O)n1cnc2c(nc(nc12)C#Cc1ccc(Cl)s1)N(C)C
    Show/Hide
Compound Formula C21H21ClN6O3S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000088 Flp-In-293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 8500 nM
   TI
   LI
   LO
   TS