Brief Information of the Compound and Protein
Compound Name
8-[4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl]-N-hydroxy-8-azaspiro[4.5]decane-3-carboxamide
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PubChem ID
CID: 136645417
Canonical SMILES
CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)N1CCC2(CCC(C2)C(=O)NO)CC1
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Compound Formula C27H36N6O4
Compound Structure
Protein Name
cGMP-specific 3',5'-cyclic phosphodiesterase
Protein Classification
Enzyme
>
Phosphodiesterase
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Phosphodiesterase 5
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Phosphodiesterase 5A
Uniprot ID
O76074
Gene Name
PDE5A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 12 nM
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