Brief Information of the Compound and Protein
Compound Name
3-[[4-ethoxy-3-(3-ethyl-1-methyl-7-oxo-6H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl]methyl]-N-hydroxycyclobutane-1-carboxamide
    Show/Hide
PubChem ID
CID: 137290273
Canonical SMILES
CCOc1ccc(CC2CC(C2)C(=O)NO)cc1-c1nc2c(CC)nn(C)c2c(=O)[nH]1
    Show/Hide
Compound Formula C22H27N5O4
Compound Structure
Protein Name
cGMP-specific 3',5'-cyclic phosphodiesterase
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 5
>
Phosphodiesterase 5A
Uniprot ID
O76074
Gene Name
PDE5A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS