Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl (3R,5S)-5-[[2-tert-butyl-4-(3-methoxypropylamino)pyrimidine-5-carbonyl]-(2-methylpropyl)amino]piperidine-3-carboxylate
    Show/Hide
 PubChem ID
CID: 59625307
Canonical SMILES
COCCCNc1nc(ncc1C(=O)N(CC(C)C)[C@@H]1CNC[C@@H](C1)C(=O)OC)C(C)(C)C
    Show/Hide
Compound Formula C24H41N5O4
Compound Structure
Protein Name
 Protein Info 
Renin
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P00797
Gene Name
REN
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000131 HEK293-F
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2.6 nM
   TI
   LI
   LO
   TS