Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl (3S,5R)-5-[[2-tert-butyl-4-(furan-2-ylmethylamino)pyrimidine-5-carbonyl]-(2-methylpropyl)amino]piperidine-3-carboxylate
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 PubChem ID
CID: 59625516
Canonical SMILES
COC(=O)[C@@H]1CNC[C@@H](C1)N(CC(C)C)C(=O)c1cnc(nc1NCc1ccco1)C(C)(C)C
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Compound Formula C25H37N5O4
Compound Structure
Protein Name
 Protein Info 
Renin
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P00797
Gene Name
REN
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000131 HEK293-F
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1.2 nM
   TI
   LI
   LO
   TS