Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4S)-3,3-dimethyl-N-[(2R)-3-methylbutan-2-yl]-1-(8-methylquinolin-2-yl)piperidine-4-carboxamide
    Show/Hide
 PubChem ID
CID: 121313879
Canonical SMILES
CC(C)[C@@H](C)NC(=O)[C@H]1CCN(CC1(C)C)c1ccc2cccc(C)c2n1
    Show/Hide
Compound Formula C23H33N3O
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 89 nM
   TI
   LI
   LO
   TS
CL000065 HEK293-EBNA
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS