Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10112937, Example 40
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 PubChem ID
CID: 86270720
Canonical SMILES
C[C@H]1N(CCc2c1ncn2-c1ccc(F)cn1)C(=O)c1cccc(c1Cl)C(F)(F)F
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Compound Formula C20H15ClF4N4O
Compound Structure
Protein Name
 Protein Info 
P2X purinoceptor 7
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
P2X receptor
Uniprot ID
Q64663
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 115 nM
   TI
   LI
   LO
   TS
2
IC50 = 115.2 nM
   TI
   LI
   LO
   TS
3
Ki = 7 nM
   TI
   LI
   LO
   TS