Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(6R)-2-(3-methylsulfonylphenyl)-6-propan-2-yl-5-[4-(trifluoromethyl)pyrimidin-2-yl]-4,6-dihydropyrrolo[3,4-c]pyrazole
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 PubChem ID
CID: 134154676
Canonical SMILES
CC(C)[C@H]1N(Cc2cn(nc12)-c1cccc(c1)S(C)(=O)=O)c1nccc(n1)C(F)(F)F
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Compound Formula C20H20F3N5O2S
Compound Structure
Protein Name
 Protein Info 
Oxysterols receptor LXR-beta
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
P55055
Gene Name
NR1H2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 7 nM