Brief Information of the Compound and Protein
Compound Name
(E)-N-[4-[4-(pyridin-2-ylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
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PubChem ID
CID: 134150618
Canonical SMILES
O=C(Nc1cc2c(Nc3ccc(Cc4ccccn4)cc3)ncnc2cn1)\C=C\CN1CCCC1
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Compound Formula C27H27N7O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P52333
Gene Name
JAK3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS