Brief Information of the Compound and Protein
Compound Name
(E)-4-(dimethylamino)-N-[4-[4-(pyridin-2-ylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
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PubChem ID
CID: 134150331
Canonical SMILES
CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(Cc4ccccn4)cc3)ncnc2cn1
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Compound Formula C25H25N7O
Compound Structure
Protein Name
Receptor tyrosine-protein kinase erbB-4
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
Q15303
Gene Name
ERBB4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 4 nM
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