Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Faridak
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 PubChem ID
CID: 6918837
SID: 15274143
Canonical SMILES
Cc1[nH]c2ccccc2c1CCNCc1ccc(\C=C\C(=O)NO)cc1
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Compound Formula C21H23N3O2
Compound Structure
Protein Name
 Protein Info 
Histone deacetylase 8
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class I
Uniprot ID
Q9BY41
Gene Name
HDAC8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4
 Cell Line Info 
Trichoplusia ni (Cabbage looper)  1
1
IC50 = 19.79 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 4.86 nM
   TI
   LI
   LO
   TS
2
IC50 = 231 nM
   TI
   LI
   LO
   TS
3
IC50 = 280 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM
2 IC50 = 277 nM
3 IC50 = 550 nM
4 IC50 = 1780 nM
5 IC50 = 1864 nM
6 IC50 < 300 nM
7 Ki = 22 nM
8 Ki = 105 nM
9 Ki = 170 nM