Brief Information of the Compound and Protein
Compound Name
(5-(4-chloro-3-(1-methyl-1H-benzo[d]imidazol-2-yl)phenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)(pyrrolidin-1-yl)methanone
    Show/Hide
PubChem ID
CID: 127048731
Canonical SMILES
Cn1c(-c2cc(N3CCc4sc(C(=O)N5CCCC5)cc4C3)ccc2Cl)nc2ccccc21
    Show/Hide
Compound Formula C26H25ClN4OS
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
>
Frizzled family G protein-coupled receptor
>
Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 315 nM
   TI
   LI
   LO
   TS