Brief Information of the Compound and Protein
Compound Name
3-[2-fluoro-4-[[3-[2-methyl-4-[2-[2-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]ethoxy]ethoxy]phenyl]phenyl]methoxy]phenyl]propanoic acid
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PubChem ID
CID: 127051856
Canonical SMILES
Cc1cc(OCCOCCNc2ccc([N+]([O-])=O)c3nonc23)ccc1-c1cccc(COc2ccc(CCC(O)=O)c(F)c2)c1
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Compound Formula C33H31FN4O8
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000460 Flp-In-T-REx-293 Homo sapiens (Human)  3
1
EC50 = 187 nM
   TI
   LI
   LO
   TS
2
Kd = 4 nM
   TI
   LI
   LO
   TS
3
Kd = 7.4 nM
   TI
   LI
   LO
   TS