Brief Information of the Compound and Protein
Compound Name
3-[2-fluoro-4-[[3-[2-methyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methylamino]phenyl]propanoic acid
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PubChem ID
CID: 60195125
SID: 144201448
Canonical SMILES
Cc1cc(OCCCS(C)(=O)=O)ccc1-c1cccc(CNc2ccc(CCC(O)=O)c(F)c2)c1
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Compound Formula C27H30FNO5S
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000460 Flp-In-T-REx-293 Homo sapiens (Human)  2
1
EC50 = 9.12 nM
   TI
   LI
   LO
   TS
2
Ki = 4.365 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  3
1
EC50 = 14.13 nM
   TI
   LI
   LO
   TS
2
EC50 = 45.71 nM
   TI
   LI
   LO
   TS
3
EC50 = 1949.84 nM
   TI
   LI
   LO
   TS