Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[5-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridin-3-yl]-6-ethylpyrimidin-2-amine
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 PubChem ID
CID: 44596118
SID: 87328372
Canonical SMILES
CCc1cc(nc(N)n1)-c1c[nH]c2ncc(cc12)-c1cnn(CCN(C)C)c1
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Compound Formula C20H24N8
Compound Structure
Protein Name
 Protein Info 
3-phosphoinositide-dependent protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase PDK1 subfamily
Uniprot ID
O15530
Gene Name
PDPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 14000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 82 nM