Brief Information of the Compound and Protein
Compound Name
(E)-1-[3-[[2-(3,4-dimethoxyphenyl)quinazolin-4-yl]amino]phenyl]-3-(4-methoxyphenyl)prop-2-en-1-one
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PubChem ID
CID: 127044753
Canonical SMILES
COc1ccc(\C=C\C(=O)c2cccc(Nc3nc(nc4ccccc34)-c3ccc(OC)c(OC)c3)c2)cc1
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Compound Formula C32H27N3O4
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000135 A2780ADR Homo sapiens (Human)  1
1
IC50 = 1290 nM
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