Brief Information of the Compound and Protein
Compound Name
3-[(1R,9R,13R)-4-hydroxy-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-10-yl]-N-isoquinolin-5-ylpropanamide
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PubChem ID
CID: 127046954
Canonical SMILES
C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCC(=O)Nc1cccc2cnccc12
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Compound Formula C26H29N3O2
Compound Structure
Protein Name
Kappa-type opioid receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001020 EE-HEK293 Homo sapiens (Human)  1
1
Ki = 2900 nM
   TI
   LI
   LO
   TS