Brief Information of the Compound and Protein
Compound Name
2-(3,4-Dichlorophenyl)-1-{(4aRS,8SR,8aRS)-4-[(pyridin-3-yl)-methyl]-8-(pyrrolidin-1-yl)perhydrochinoxalin-1-yl}ethan-1-one
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PubChem ID
CID: 68775633
Canonical SMILES
O=C(Cc1ccc(Cl)c(Cl)c1)N1CCN(Cc2cccnc2)C2CCCC(N3CCCC3)C21
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Compound Formula C26H32Cl2N4O
Compound Structure
Protein Name
Kappa-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 34 nM
   TI
   LI
   LO
   TS
2
Ki = 22 nM
   TI
   LI
   LO
   TS