Brief Information of the Compound and Protein
Compound Name
1'-{(3,4-dihydro-2H-chromen-3-yl)methyl}-2,3-dihydro-1'H-spiro[indene-1,4'-piperidine]
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PubChem ID
CID: 127034022
Canonical SMILES
c1ccc2c(c1)CC(CN1CCC3(CCc4ccccc43)CC1)CO2
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Compound Formula C23H27NO
Compound Structure
Protein Name
Nociceptin receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41146
Gene Name
OPRL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 122 nM
   TI
   LI
   LO
   TS
2
Ki = 5.65 nM
   TI
   LI
   LO
   TS