Brief Information of the Compound and Protein
Compound Name
3-{(2,3-Dihydro-1'H-spiro[indene-1,4'-piperidin]-1'-yl)methyl}-1,2,3,4-tetrahydroisoquinolin-6-ol
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PubChem ID
CID: 11552010
SID: 16654241
Canonical SMILES
Oc1ccc2c(c1)CC(CN1CCC3(CCc4ccccc43)CC1)NC2
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Compound Formula C23H28N2O
Compound Structure
Protein Name
Nociceptin receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41146
Gene Name
OPRL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 227 nM
   TI
   LI
   LO
   TS
2
Ki = 10.2 nM
   TI
   LI
   LO
   TS