Brief Information of the Compound and Protein
Compound Name
5-chloro-3-[[4-(4-fluoro-2-methylphenyl)piperidin-1-yl]methyl]-1,2,3,4-tetrahydroisoquinolin-8-ol
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PubChem ID
CID: 127033703
Canonical SMILES
Cc1cc(F)ccc1C1CCN(CC2Cc3c(Cl)ccc(O)c3CN2)CC1
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Compound Formula C22H26ClFN2O
Compound Structure
Protein Name
Nociceptin receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41146
Gene Name
OPRL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 28.7 nM
   TI
   LI
   LO
   TS
2
Ki = 3.13 nM
   TI
   LI
   LO
   TS