Brief Information of the Compound and Protein
Compound Name
5-chloro-3-(spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylmethyl)-1,2,3,4-tetrahydroisoquinolin-8-ol
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PubChem ID
CID: 11516508
SID: 16618487
Canonical SMILES
Oc1ccc(Cl)c2CC(CN3CCC4(CCc5ccccc45)CC3)NCc12
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Compound Formula C23H27ClN2O
Compound Structure
Protein Name
Nociceptin receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41146
Gene Name
OPRL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 21.3 nM
   TI
   LI
   LO
   TS
2
Ki = 2.2 nM
   TI
   LI
   LO
   TS