Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3S,6S,9S,12S,18S)-18-((2S,5S,8S,11S,14S,17S,20S,23R,26S,29S,32S)-20-((1H-imidazol-5-yl)methyl)-54-amino-23-benzyl-8-(2-carboxyethyl)-32-(carboxymethyl)-11-(3-guanidinopropyl)-26-((R)-1-hydroxyethyl)-2,14,17,29-tetraisobutyl-5-isopropyl-4,7,10,13,16,19,22,25,28,31,34-undecaoxo-37,40,43,46,49,52-hexaoxa-3,6,9,12,15,18,21,24,27,30,33-undecaazatetrapentacontanamido)-3-((2S)-5-amino-1-(1-((2S)-1-((2S)-5-amino-1-((6S,9S,18S)-18-((3S,6S,9S,12S,18S,24S,25S)-1-amino-9-(4-aminobutyl)-15-butyl-24-carbamoyl-18-(2-carboxyethyl)-6-(3-guanidinopropyl)-12-isobutyl-21,21,25-trimethyl-1,4,7,10,13,16,19,22-octaoxo-5,8,11,14,17,20,23-heptaazaheptacosan-3-ylcarbamoyl)-3,3,6-trimethyl-2,5,8,12-tetraoxo-1,4,7,13-tetraazacyclooctadecan-9-ylamino)-1,5-dioxopentan-2-ylamino)-1-oxopropan-2-ylamino)-2-methyl-1-oxopropan-2-ylamino)-1,5-dioxopentan-2-ylcarbamoyl)-15-butyl-9-(3-guanidinopropyl)-6,12-dimethyl-5,8,11,14,17-pentaoxo-4,7,10,13,16-pentaazaicosane-1,20-dicarboxylic acid
    Show/Hide
 PubChem ID
CID: 145948644
Canonical SMILES
CCCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H]1CCCCNC(=O)CC[C@@H](NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](C)NC(=O)C(C)(C)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](C)NC(=O)C(CCCC)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CC(=O)O)NC(=O)CCOCCOCCOCCOCCOCCOCCN)[C@@H](C)O)C(C)C)C(=O)N[C@H](C)C(=O)NC(C)(C)C(=O)N1)C(=O)N[C@@H](CCC(=O)O)C(=O)NC(C)(C)C(=O)N[C@H](C(N)=O)[C@@H](C)CC
    Show/Hide
Compound Formula C184H313N51O55
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 2
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Corticotropin releasing factor receptor
>
Corticotropin releasing factor receptor
Uniprot ID
Q60748
Gene Name
CRHR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000583 COS-M6
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  2
1
Ki = 1.07 nM
   TI
   LI
   LO
   TS
2
Ki = 2.11 nM
   TI
   LI
   LO
   TS